Challenge 2.1: Substitution strategies

Substitution with safer alternatives is at the top of the hierarchy of measures to prevent exposure to cancer causing agents at work and collecting substitution and innovation examples will provide help to companies in search for their successful substitution plan.

Substitution of hazardous chemicals with safer alternatives is at the top of the hierarchy of measures to prevent chemical risks at work, including the prevention of occupational cancers. Substitution is also a driver for innovation and a transition to chemicals that are safer for human health and the environment. It also links with the European Commission’s priorities for 2019-24 and the European Green Deal with the Chemicals strategy. The Roadmap on Carcinogens will aim to collect and disseminate more information on successful substitutions, to link with experts on substitution, and help understand how frontrunner companies have substituted substances of concern from their supply chain and developed opportunities for innovation. It will reach out to the administrators of the main databases on substitution to explore the best ways of getting substitution solutions to the workplaces.


Challenge Team

  • ETUI (challenge lead), Belgium


  • Member States
  • Organisations working on Substitution (both EU and national level)
  • Employers’ and Workers’ organisations
  • Frontrunner companies
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Challenge updates

Progress report

July 28, 2021

Tools to support the employer with their risk assessment are available for example in France and Germany. Within Challenge 3.2 – Involving Occupation prevention organisations, the first activity included identifying other tools in the EU and publishing a non-exhaustive overview. After the data generation, we can conclude that the assessed tools share many commonalities and […]

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